Author

Margherita Guaita

Manchester Academic Health Science CentreORCID 0000-0001-8295-936XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alan M. RosemaniD· 1 shared Graham D. PavittiD· 1 shared Martin D. JenningsiD· 1 shared Tomas Adomavicius· 1 shared Yu Zhou· 1 shared Zakia LatifiD· 1 shared

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2019-2019 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Alan M. RosemanORCID

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1 paper

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedMay 13, 2019

The structural basis of translational control by eIF2 phosphorylation

Tomas Adomavicius, Margherita Guaita, Yu Zhou…·Graham D. Pavitt

This study determines the structures of phosphorylated and unphosphorylated eIF2 bound to eIF2B, revealing how eIF2 phosphorylation modulates translational control through altered binding affinity.

180 citationstop 2%

protein structureexperimental assay

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