Lise Mangiante

PATH-IC uses generative AI to predict breast cancer genomic subtypes from histology images, achieving high accuracy and correlating with clinical outcomes.

This study identifies type I interferon signaling as a tumor-intrinsic suppressor of proliferation in 3D breast cancer spheroids through RIG-I-mediated sensing of cytosolic RNA.

The paper uses spatial imaging and computational analysis to identify features in metastatic tumors that predict response to immune checkpoint inhibition in TNBC patients.

This paper presents a comprehensive molecular characterization of Malignant Pleural Mesothelioma using multi-omics data from 120 patients, integrating with existing datasets to create an interactive molecular phenotype map.