Alea C. Delmastro

The paper introduces a method to predict longitudinal outcomes from single-timepoint data using a virtual library of granulomas, applied to tuberculosis in non-human primates.

This study shows that D-1MT treatment enhances CD8+ T cell infiltration and interactions with macrophages in TB granulomas, improving immune control of Mtb.

This study identifies hypoxia as a key driver of immune dysfunction in TB granulomas, correlating with bacterial persistence.

The paper uses spatial imaging and computational analysis to identify features in metastatic tumors that predict response to immune checkpoint inhibition in TNBC patients.

This study identifies IFNγ-expressing myeloid cells in lipoproteinosis regions of sJIA-daPAP patients, suggesting their role in immune pathology.