Author

Matthew J. Beucler

University of CincinnatiORCID 0000-0001-8334-7736Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

William E. MilleriD· 2 shared Abigail L. DooleyiD· 1 shared Andrew VonHandorfiD· 1 shared Audrey Crowther· 1 shared Benjamin E. GewurziD· 1 shared Bo ZhaoiD· 1 shared Carmy R. ForneyiD· 1 shared Christine M. O’ConnoriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

William E. MillerORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedAug 31, 2026

The Human Cytomegalovirus vGPCR UL33 is Essential for Efficient Lytic Replication in Epithelial Cells

MacKenzie R. Freeman, Abigail L. Dooley, Ian J. Groves…·William E. Miller

This study shows that deletion of UL33 from HCMV genome reduces lytic replication in epithelial cells by impairing Gq-dependent signaling and gene expression.

2 citations

humanexperimental assay

𝕏 PostBluesky

GenomicseLifePeer-reviewedSep 10, 2025

Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity

Khund Sayeed, Sreeja Parameswaran, Matthew J. Beucler…·Matthew T. Weirauch

This study shows HCMV infection disrupts chromatin organization and reduces TEAD1 activity through multiple mechanisms, linking it to genetic risk loci for eye and ear development.

2 citations

humanChIP-seq

𝕏 PostBluesky