Author

Shao-Ming Shen

Shanghai Jiao Tong UniversityORCID 0000-0001-8334-9790Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:structural biology· 1

Frequent Co-Authors

Cheng ZhangiD· 1 shared Guanghui WangiD· 1 shared Guoqiang XuiD· 1 shared Jinrong MiniD· 1 shared Qin Xiao· 1 shared Xiaolei HuangiD· 1 shared Xinci ShangiD· 1 shared Xuechu ZheniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Cheng ZhangORCID

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1 paper

Recent·Most cited

Cancer BiologyCell Death and DiseasePeer-reviewedMay 14, 2024

Structural insights into specific recognition of PTENα/β-NTE by WDR5 in cancer progression

Xiaolei Huang, Cheng Zhang, Xinci Shang…·Yanli Liu

The paper determines the crystal structure of PTEN-NTE bound to WDR5, revealing a specific binding motif that promotes tumor growth and suggests WDR5 inhibitors as potential cancer therapies.

8 citations

structural biologyexperimental assay

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