NeurosciencebioRxivPreprint
Plasma Membrane Calcium Atpase downregulation in dopaminergic neurons alters cellular physiology and behavior in Drosophila melanogaster
Brenda Erhardt, María Celeste Leal, María Silvina Marcora…·Fernando Juan Pitossi
This study downregulates PMCA in dopaminergic neurons of Drosophila to model Parkinson's Disease, finding increased calcium, oxidative stress, locomotor changes, and lifespan reduction.
DOI 10.1101/714147