Author

Neal A. DeLuca

University of PittsburghORCID 0000-0001-8381-8577Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Sarah E. DremeliD· 2 shared Britt A. GlaunsingeriD· 1 shared Frances L. Sivrich· 1 shared Jessica M. TuckeriD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersMolecular Biology

Sarah E. DremelORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedFeb 2, 2022

Manipulation of RNA Polymerase III by Herpes Simplex Virus-1

Sarah E. Dremel, Frances L. Sivrich, Jessica M. Tucker…·Neal A. DeLuca

This study investigates how HSV-1 manipulates RNA Polymerase III by increasing tRNA expression and altering transcriptional machinery interactions.

40 citations

humanbulk RNA-seq

GenomicseLifePeer-reviewedOct 22, 2019

Herpes Simplex nucleoprotein creates a competitive environment facilitating robust viral transcription and host shut off

Sarah E. Dremel, Neal A. DeLuca

This study identifies HSV-1 ICP4 as a key factor in recruiting host transcription machinery to the viral genome, leading to host transcriptional shut off.

69 citationstop 3%

experimental assay