Systems BiologyInternational Journal of Molecular SciencesPeer-reviewed
Connectivity analysis of single cell RNA-sequencing derived transcriptional signature of lymphangioleiomyomatosis
Naim Al Mahi, Erik Y. Zhang, Susan G. Sherman…·Mario Medvedovic
The paper develops methods to construct disease transcriptional signatures and perform connectivity analysis using scRNA-seq data, identifying mTORC1 and other inhibitors as potential therapies for LAM.