Naim Al Mahi

The paper identifies treatment response-associated cell subpopulations in autoimmune diseases by integrating single-cell and bulk data from IBD and PsO patients, revealing key pathways and cell types involved in response or non-response.

A genome-wide CRISPR screen and genetic analysis identify TNRC18 as a novel regulator of IL-1β production and a risk factor for inflammatory diseases.

iLINCS provides a web-based platform for analyzing omics signatures of diseases and cellular perturbations through integrative analytics and visualization tools.

The paper develops methods to construct disease transcriptional signatures and perform connectivity analysis using scRNA-seq data, identifying mTORC1 and other inhibitors as potential therapies for LAM.

GREIN provides a web platform for re-analyzing GEO RNA-seq data with tools for data manipulation, visualization, and functional analysis.