Author

Atom J. Lesiak

University of WashingtonORCID 0000-0001-8413-6340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

John F. NeumaieriD· 3 shared Kevin R. CoffeyiD· 3 shared Gwenn A. GardeniD· 2 shared Aliyah J. Dawkins· 1 shared Brett D. Dufour· 1 shared Emily K. Vo· 1 shared Marjorie R. LevinsteiniD· 1 shared Rapheal G. Williams· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

John F. NeumaierORCID

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3 papers

Recent·Most cited

NeuroscienceNeurobiology of StressPeer-reviewedNov 1, 2020

Stress induces divergent gene expression among lateral habenula efferent pathways

Marjorie R. Levinstein, Kevin R. Coffey, Ruby E. Marx…·John F. Neumaier

The paper examines how stress affects gene expression in different pathways of the lateral habenula in rats, finding divergent translatome changes, particularly in RMTg-projecting neurons.

12 citations

ratbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 2, 2020

Chronic Intermittent Ethanol Activates CHOP in Striatal Microglia and Exacerbates Ethanol Withdrawal

Rapheal G. Williams, Brett D. Dufour, Kevin R. Coffey…·John F. Neumaier

This study investigates how chronic intermittent ethanol affects microglial translatome in striatum, identifying CHOP and UPR as key factors in ethanol withdrawal symptoms.

DOI 10.1101/2020.09.02.280156

mouseRibo-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 10, 2020

RiboTag-Seq Reveals a Compensatory cAMP Responsive Gene Network in Striatal Microglia induced by Morphine Withdrawal

Kevin R. Coffey, Atom J. Lesiak, Russell G. Marx…·John F. Neumaier

The paper uses RiboTag-Seq to show that morphine withdrawal induces a cAMP-responsive gene network in striatal microglia, affecting their morphology and interactions with neurons.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky