Cell BiologyJournal of Biological ChemistryPeer-reviewed
A GluN2B disease-associated variant promotes degradation of NMDA receptors via autophagy
Taylor M. Benske, Marnie P Williams, Pei-Pei Zhang…·Ting‐Wei Mu
The paper shows that the R519Q GluN2B variant is degraded via autophagy-lysosomal pathway, providing a mechanism for NMDAR variant clearance and potential therapeutic targets.
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