Author

Ian Denis Fisk

University of NottinghamORCID 0000-0001-8448-3123Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:plant (other)· 1

Frequent Co-Authors

Iain Robert SearleiD· 2 shared Aneesh LaleiD· 1 shared John Michael FoulkesiD· 1 shared Jozef GécziD· 1 shared Karthik Shantharam KamathiD· 1 shared Luqman Bin SafdariD· 1 shared Marianna PasquarielloiD· 1 shared Pei Qin NgiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

Iain Robert SearleORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyScientific ReportsPeer-reviewedDec 11, 2025

TMT-based quantitative proteomic assessment of Vicia sativa induced neurotoxicity by β-cyano-L-alanine and γ-glutamyl-β-cyano-L-alanine in SH-SY5Y cells.

Samuel Riley, Vy Nguyen, Rudrarup Bhattacharjee…·Iain Robert Searle

This study uses TMT-based proteomics to analyze the effects of BCA and GBCA on SH-SY5Y cells, identifying distinct dysregulated proteins and pathways associated with neurotoxicity.

DOI 10.1038/s41598-025-30121-2

humanproteomics

𝕏 PostBluesky

Plant BiologybioRxivPreprintOct 10, 2025

Mutations in HOMEOBOX DOMAIN-2 improve grain protein content in wheat without significantly affecting grain yield and senescence

Luqman Bin Safdar, Ian Denis Fisk, Marianna Pasquariello…·Scott A. Boden

This study evaluates mutations in HB-2 in wheat, finding they improve grain protein content without reducing yield or accelerating senescence.

DOI 10.1101/2025.10.10.681749

plant (other)bulk RNA-seq

𝕏 PostBluesky