Hao H. Sun

The paper presents an xQTL atlas of regulatory variation in the aging human brain, integrating multiple modalities and cell types across four studies, identifying more variant-molecular-trait associations by including TAD boundaries.

This paper introduces FGMB, a multi-context regulome-wide association atlas, and applies it to Alzheimer's disease to identify 327 regulatory associations and resolve 86 gene-molecular-trait pairs.

fSuSiE improves fine-mapping of QTLs by modeling spatial genetic effects on molecular traits, achieving higher resolution in identifying causal variants and their molecular targets.