Jill A. Macoska

The paper uses multi-omics analysis to study molecular changes in the bladder after spinal cord injury in rats and identifies DNA damage response pathways modulated by inosine treatment.

This study shows that voluntary exercise reduces tumor growth in a mouse model of castration-resistant prostate cancer by affecting DNA replication, AR signaling, and mitochondrial dynamics.

This paper introduces a Bayesian model to infer transcription factor activity from gene expression data using logical rules and applies it to bulk and single-cell transcriptomics to study fibroblast plasticity.

The paper introduces CIE, a platform for causal inference of active transcriptional regulators using differential gene expression data and a regularized Gaussian Graphical Model.