Tau hyperphosphorylation impairs cooperative binding tomicrotubules and perturbs organelle trafficking in neurons
Daniel Beaudet, Christopher L. Berger, Adam G. Hendricks
This study shows that tau hyperphosphorylation disrupts cooperative microtubule binding and impairs lysosome trafficking in neurons, contributing to neurodegeneration.
Biophysical Journal · Feb 1, 2025Peer-reviewedBiophysics