Robin P. Wharton

The paper identifies mRNAs regulated by Nanos in Drosophila embryos, showing it targets over 2600 mRNAs in collaboration with Pum, many of which are stabilized in nos- embryos and hypo-adenylated.

This study shows that the N-terminal domains of Drosophila Pumilio and Nanos play significant roles in NRE recognition through trans and cis mechanisms.