Author

Alexander Bampton

Instituto de Investigación Biomédica de LleidaORCID 0000-0001-8529-8210Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Anna‐Leigh BrowniD· 2 shared Matteo ZanovelloiD· 2 shared Matthew J. KeussiD· 2 shared Pietro FrattaiD· 2 shared Tammaryn LashleyiD· 2 shared Abraham Acevedo‐ArozenaiD· 1 shared Alessandro Marrero‐GagliardiiD· 1 shared Ángel AcebesiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Anna‐Leigh BrownORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 23, 2024

A functional interaction between TDP-43 and USP10 reveals USP10 dysfunction in TDP-43 proteinopathies

Alessandro Marrero‐Gagliardi, Judith Noda, Matteo Zanovello…·Abraham Acevedo‐Arozena

This study identifies a functional interaction between TDP-43 and USP10, showing USP10 modulates alternative splicing and can reduce TDP-43 toxicity in a mouse model of ALS and FTD.

1 citation

humanproteomics

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NeurosciencebioRxivPreprintApr 2, 2021

Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization

Anna‐Leigh Brown, Oscar G. Wilkins, Matthew J. Keuss…·Pietro Fratta

The paper shows that ALS/FTD risk variants in UNC13A increase sensitivity to TDP-43 depletion by promoting cryptic exon inclusion and protein loss.

13 citations

humanbulk RNA-seq

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