Veronica Tozzo

The paper identifies a founder variant in ADAP1 associated with increased risk of schizophrenia and bipolar disorder in a Colombian genetic isolate.

This study evaluates the GIRA approach in a health system, finding 30.4% of patients labeled high-risk based on genomic data, with ancestry differences and social deprivation influences.

The paper analyzes genetic and health record data from a diverse population to uncover gene-phenotype associations and assess polygenic score performance across ancestries.

This study shows that inclusion biases in biobanks affect genetic analysis results and suggests using inverse probability weighting to improve variant discovery and replication.

This study investigates genetic factors influencing weight loss from GLP1-RA and bariatric surgery in 10,960 individuals across 9 biobanks, finding no strong genetic associations with GLP1-RA effectiveness but a modest link between BMI polygenic scores and reduced bariatric surgery weight loss.

This study identifies a 3-fold kernel signature for Alzheimer's Disease using GWAS data, highlighting SNPs, genes, and pathways associated with AD risk.