Chromosome 2q31.2 Deletion Impairs Neuronal Plasticity through Integrated Stress Response Activation
Brooke Naomi Nakamura, Saman Sedighi, Diganta Das, Radhika M. Joshi, Josh Neman
This study investigates how a chromosome 2q31.2 deletion affects neuronal plasticity by activating the integrated stress response (ISR) and shows that ISR inhibition improves neuronal function.
bioRxiv · Apr 28, 2026 · PreprintNeuroscience