Josh Neman

This study develops a microneurosurgical platform in mice to model brain tumor recurrence and metastasis, revealing molecular changes in relapsed tumors.

This study investigates how a chromosome 2q31.2 deletion affects neuronal plasticity by activating the integrated stress response (ISR) and shows that ISR inhibition improves neuronal function.

The paper shows HDAC1 inhibition in MDSCs increases Malat1, decreases pSTAT3, induces apoptosis and cell cycle arrest, and reduces T cell suppression.

The paper identifies HTR2B on MDSCs as a target to enhance immune checkpoint inhibitors in breast-to-brain metastasis using clozapine and anti-PD-1 therapy.