NeurosciencebioRxivPreprint
Blood-based Transcriptomics Reveal Sex- and Amyloid-Modulated Biology of Plasma pTau217 in Preclinical Alzheimer's Disease
Mabel Seto, Hannah M Klinger, Michelle J. Clifton…·Rachel F. Buckley
The paper identifies gene associations with plasma pTau217 in preclinical Alzheimer's disease, showing modulation by APOEε4, Aβ-PET, and sex, with X-linked genes playing a role.
DOI 10.1101/2025.11.21.689770