Monica C. Pillon

This study characterizes the molecular architecture of the human RNA Degradosome and identifies key features governing SUV3-PNPase complex formation.

TAMALE identifies functional residues across the human proteome using structure models and variant effect predictions, validated through case studies and experimental validation.

This study identifies the functional roles of two HEPN motifs in Las1, showing both are required for nuclease activity and specificity in RNA cleavage.

This study identifies the molecular features and spatial organization of the human Las1L-Nol9 complex involved in ITS2 pre-rRNA processing.