Author
National Institutes of HealthORCID 0000-0002-7500-7077Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Yukitomo Arao, Jason Grant Williams, Wi S. Lai
The paper investigates TTP's role in reducing ARE-containing mRNA levels through interactions with CNOT10, distinct from its known mRNA decay function.
Elise B. Dunshee, Brenna A Saladin, David J. Turner…·Aaron C. Goldstrohm
The paper identifies how human PUM proteins repress mRNAs by using fuzzy multivalent hydrophobic interactions to recruit the CCR4-NOT deadenylase complex through their intrinsically disordered RD3 domain.
Masataka Suzawa, Chen Qiu, Ahsan Habib Polash…·Markus Hafner
The paper identifies an RNA sequence motif recognized by the DND1-NANOS3 complex in germ cells and shows its role in regulating mRNA expression.
Chiara Klöckner, J. Pedro Fernández-Murray, Mahtab Tavasoli…·Konrad Platzer
The paper identifies bi-allelic CHKA variants causing a neurodevelopmental disorder with epilepsy and microcephaly through functional analysis in yeast.
Monica C. Pillon, Kevin H. Goslen, Jason Grant Williams, Robin Evans Stanley
This study identifies the functional roles of two HEPN motifs in Las1, showing both are required for nuclease activity and specificity in RNA cleavage.