Author

Laurent Tiret

InsermORCID 0000-0001-8573-8335Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Inès BarthélémyiD· 2 shared Nicolas Blanchard‐GuttoniD· 2 shared Stéphane BlotiD· 2 shared Ambre CourtiniD· 1 shared Andrea Carlier· 1 shared Caroline Dufaure de CitresiD· 1 shared Catherine EscriouiD· 1 shared Dennis P O’BrieniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Inès BarthélémyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A missense variant in PAOX in American Staffordshire Terriers with juvenile-onset polyneuropathy

Lucie Chevallier, Garrett Bullock, Thibaut Troupel, Nicolas Blanchard‐Gutton, Inès Barthélémy, Kaspar Matiasek, Frank Steffen, Ambre Courtin, Liz Hansen, Matthias Christen, Vidhya Jagannathan, Caroline Dufaure de Citres, Marion Signoret, Catherine Escriou, Marie Abitbol, , Martin L. Katz

This paper identifies a missense variant in the PAOX gene as the cause of juvenile-onset polyneuropathy in American Staffordshire Terriers, highlighting its potential as a model for human Charcot-Marie-Tooth disease.

bioRxiv · Oct 16, 2025 · PreprintGenetics

CRISPR/Cas13-mediated Dynamin 2 reduction therapy in a canine model of DNM2-related centronuclear myopathy

Andrea Carlier, Inès Barthélémy, Nicolas Blanchard‐Gutton, Sophie Château‐Joubert, Frédéric Aurade, Teoman Ozturk, Nathalie Didier, Frédéric Relaix, Laurent Tiret, Stéphane Blot, Isabel Punzón

This study demonstrates that CRISPR/Cas13-mediated reduction of DNM2 expression can alleviate CNM symptoms in a canine model.

bioRxiv · Sep 5, 2025 · PreprintMolecular Biology