Jacob Morrison

Tranquillyzer is a deep learning framework for processing long-read single-cell RNA-seq data, enabling accurate identification of structural elements and demultiplexing despite sequencing errors and library variability.

The paper introduces scDEEP-mC, a single-cell DNA methylation profiling method, and shows it can identify cell types, X-inactivation states, and replication dynamics with high coverage.

Synthbar adds synthetic cell barcodes to sequencing reads to enable compatibility with computational tools that require them.

STORM-seq improves single-cell RNA sequencing by enhancing detection of non-coding transcripts and transcript-level complexity, revealing new cell states in human fallopian tube epithelium.