Author

Lillian Barra

Western UniversityORCID 0000-0001-8614-6972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

Ewa CairnsiD· 2 shared Gabrielle Buckley· 2 shared Jaspreet KauriD· 1 shared Lisa Cameron· 1 shared S. M. Mansour HaeryfariD· 1 shared Sheri Saunders· 1 shared Sofya UlanovaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

Ewa CairnsORCID

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2 papers

Recent·Most cited

Homocitrullinated Peptides Drive Pro-Inflammatory T-Cell Responses in a Humanized Mouse Model of Rheumatoid Arthritis

Sofya Ulanova, Jaspreet Kaur, Gabrielle Buckley, S. M. Mansour Haeryfar, Lisa Cameron, Ewa Cairns, Lillian Barra

This study shows that a homocitrullinated peptide induces pro-inflammatory T-cell responses in a humanized mouse model of rheumatoid arthritis, suggesting a role in disease pathogenesis.

Arthritis & Rheumatology · Jun 8, 2026Peer-reviewedImmunology

Immune Responses Targeting Homocitrullinated Peptides Drive Rheumatoid Arthritis-like Pathology in HLA-DR4 Transgenic Mice

Gabrielle Buckley, Sheri Saunders, Ewa Cairns, Lillian Barra

This study shows that homocitrulline-specific immune responses induce RA-like pathology in HLA-DR4 transgenic mice, supporting the pathogenic role of anti-homocitrullinated protein autoantibodies in RA.

bioRxiv · Sep 17, 2025 · PreprintImmunology