Stephen Makin

APOE4 genotype, blood-brain barrier leakage and ischaemic stroke subtype and location

This study examines the association between APOE4 genotype, BBB permeability, and infarct distribution in patients with mild ischemic stroke, finding a posterior-predominant infarct distribution in APOE4 carriers despite similar BBB metrics.

Prediction of white matter hyperintensities evolution one-year post-stroke from a single-point brain MRI and stroke lesions information

This paper predicts one-year WMH evolution post-stroke using MRI and stroke lesion data with a probabilistic deep learning model, achieving improved accuracy through joint segmentation and a new loss function.

Automatic Spatial Estimation of White Matter Hyperintensities Evolution in Brain MRI using Disease Evolution Predictor Deep Neural Networks

This paper introduces DEP models to predict white matter hyperintensity evolution in brain MRI, showing that semi-supervised models with Gaussian noise inputs perform best.

Predicting the Evolution of White Matter Hyperintensities in Brain MRI using Generative Adversarial Networks and Irregularity Map

This paper introduces DEP-GAN, a GAN model that predicts WMH evolution in small vessel disease using irregularity maps and two discriminators, achieving 72.01% accuracy in predicting WMH evolution.