Deepali Vasoya

The paper compares two iPSC-microglia protocols to assess how the MAPT-S305N mutation affects microglial function and neuronal health in a frontotemporal dementia model.

This study examines the association between APOE4 genotype, BBB permeability, and infarct distribution in patients with mild ischemic stroke, finding a posterior-predominant infarct distribution in APOE4 carriers despite similar BBB metrics.

This study shows astrocytes alter the transcriptomic and epigenetic landscape of developing cortical neurons, promoting intrinsic excitability and influencing disease-related pathways.

The paper shows that wild-type bone marrow-derived microglia-like cells reduce strain-dependent neuropathology in Csf1r mutant mice by preventing thalamic calcification.

This study shows that neurodevelopmental processes in the cortex and thalamus can occur normally without microglia, using a genetically modified mouse model.

This study shows microglia promote beta-amyloid plaque formation but are not required for subsequent pathological changes in Alzheimer's disease.

The paper integrates immunopeptidomics and immunoinformatics to characterize BoLA-DR antigen presentation and identify CD4 T cell epitopes with high predictive accuracy.