Author

Francesca M. Chappell

University of EdinburghORCID 0000-0002-7742-1757Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:imaging· 3 Approach:statistical model· 3 Research Focus:differential expression· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Joanna Marguerite WardlawiD· 3 shared Maria del Carmen Valdés HernándeziD· 2 shared Michael J. ThrippletoniD· 2 shared David Alexander DickieiD· 1 shared Deepali VasoyaiD· 1 shared Fergus DoubaliD· 1 shared Gordon W. BlairiD· 1 shared Ian J. DearyiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersNeuroscience

Joanna Marguerite WardlawORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 10, 2026

APOE4 genotype, blood-brain barrier leakage and ischaemic stroke subtype and location

Krystal K. Laing, Maria del Carmen Valdés Hernández, Michael J. Thrippleton…·Joanna Marguerite Wardlaw

This study examines the association between APOE4 genotype, BBB permeability, and infarct distribution in patients with mild ischemic stroke, finding a posterior-predominant infarct distribution in APOE4 carriers despite similar BBB metrics.

DOI 10.64898/2026.06.05.730537

humanimaging

𝕏 PostBluesky

NeuroscienceFrontiers in NeurologyPeer-reviewedJul 25, 2019

Spatial Gradient of Microstructural Changes in Normal-Appearing White Matter in Tracts Affected by White Matter Hyperintensities in Older Age

Susana Muñoz Maniega, Rozanna Meijboom, Francesca M. Chappell…·Joanna Marguerite Wardlaw

The paper quantifies microstructural changes in normal-appearing white matter near white matter hyperintensities in older adults, showing spatial gradients of damage linked to WMH burden.

33 citations

humanimaging

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 11, 2019

Intracranial functional haemodynamic relationships in patients with cerebral small vessel disease

Gordon W. Blair, Michael J. Thrippleton, Yulu Shi…·Joanna Marguerite Wardlaw

This study examines how cerebral blood flow and vascular pulsatility relate to cerebral small vessel disease features in patients with minor ischaemic stroke.

4 citations

humanimaging

𝕏 PostBluesky