Yuchen Wang

TriStageHLA improves epitope prioritization by integrating peptide screening, binding prediction, and immunogenicity assessment with high accuracy and efficiency.

This study uses spatial multi-omics to compare EBV-positive and EBV-negative cHL, identifying distinct TME features and immunological signatures linked to EBV.

scCAFE is a deep learning model that detects multi-scale chromatin architectural features in single-cell Hi-C data, outperforming existing methods and enabling cell-type annotation from 3D genome features.