Author

Charles E. Booth

East Carolina UniversityORCID 0000-0001-8737-4627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alexandra D. Powell-PierceiD· 1 shared Brandon L. GarciaiD· 1 shared Brittany L. ShapiroiD· 1 shared Jon T. SkareiD· 1 shared Payton Smith· 1 shared Shannon Sedberry Allen· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Alexandra D. Powell-PierceORCID

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1 paper

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedJul 24, 2025

The dual activity of BBK32: Implications for simultaneous inhibition of borrelial-specific antibody-dependent complement activation and fibronectin binding

Alexandra D. Powell-Pierce, Charles E. Booth, Payton Smith…·Jon T. Skare

This paper demonstrates that BBK32, a surface protein of Borreliella burgdorferi, simultaneously inhibits complement activation by binding C1r and binds fibronectin, aiding in immune evasion and dissemination.

3 citations

humanexperimental assay

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