Author

David M. Alvarado

Washington University in St. LouisORCID 0000-0001-8748-0761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashley C. King· 1 shared Kerry A. SwansoniD· 1 shared Kristen M. SeileriD· 1 shared Matthew A. CiorbaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

Ashley C. King

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1 paper

Recent·Most cited

IBD risk locus rs1077773 is a pharmacogenomic eQTL for aryl hydrocarbon receptor activity and modulates immune cell function.

Ashley C. King, Kristen M. Seiler, Kerry A. Swanson, Matthew A. Ciorba, David M. Alvarado

This paper identifies rs1077773 as a pharmacogenomic eQTL for AHR activity, showing it enhances transcriptional activity in organoids and reduces inflammatory cytokine production in macrophages.

bioRxiv · Sep 26, 2025 · PreprintCell Biology