Eduardo J. Caleiras

This study identifies NGFR as a regulator of immune evasion in HNSCC, showing that its inhibition enhances antigen presentation and CD8+ T cell response to checkpoint blockade.

This study identifies NGFR as a marker of a basal BLCA subpopulation associated with poor prognosis and reduced immunotherapy response.

This study shows that CCNY overexpression causes a fatal metabolic syndrome by disrupting glucose homeostasis and inducing a Warburg-like metabolic shift.

This paper shows that combining three KRAS signaling pathway inhibitors effectively regresses pancreatic tumors and prevents resistance in preclinical models.

The paper shows that transient CB2R activation in breast cancer cells leads to irreversible luminal differentiation through chromatin remodeling, enhancing tamoxifen response and reducing resistance.

This paper identifies a novel molecular subtype of papillary renal cell carcinoma (pRCC) characterized by HIF-pathway overactivation, associated with poor prognosis and distinct biological features.

This study identifies Hnrnpk as a master regulator of nucleolar stress and ribosome impairment, linking nucleolar abnormalities to aging and bone marrow failure.