María Velasco‐Estevez

PepSpace designs specific peptides using physics-driven directed evolution, achieving stronger predicted interactions and better binding specificity than machine learning models.

This study identifies how RNA-regulated fusion dynamics of hnRNPK-based nucleolar condensates prevent coalescence and maintain size control.

This study shows that MYC overexpression in CLL worsens prognosis and treatment response, with different effects based on TP53 status.

This study identifies PIEZO1 as an oncogene in glioma that promotes astrocyte reactivity and is associated with worse prognosis in male patients.

This study identifies Hnrnpk as a master regulator of nucleolar stress and ribosome impairment, linking nucleolar abnormalities to aging and bone marrow failure.

The paper investigates TDAG8 expression and function in oligodendrocytes under acidic conditions and inflammation, finding upregulation during maturation and in MS lesions.