BiochemistrybioRxivPreprint
Mechanisms involved in the lipid membrane tubulation activity of the pH-responsive MakA protein from Vibrio cholerae
Athar Alam, Abdelbasset Yabrag, Naeem Ullah…·Aftab Nadeem
This study identifies the molecular mechanisms of MakA's pH-dependent lipid membrane tubulation, showing that His30 protonation and cholesterol binding drive conformational changes necessary for tubulation.
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