ImmunologyeLifePeer-reviewed
Allosteric disulfide control of ligand binding and endocytosis of KIR2DL4, the natural killer cell receptor for HLA-G
Sumati Rajagopalan, Joyce Chiu, Priyanka Chaurasia…·Eric O. Long
This study identifies an allosteric disulfide bond in KIR2DL4 that regulates HLA-G binding and endocytosis, influencing NK cell function during pregnancy.
DOI 10.7554/elife.111018.3