BiochemistryAnalytical ChemistryPeer-reviewed
Rapid Histone Post-Translational Modification Analysis Using Alternative Proteases and Tandem Mass Tags
Natalie P. Turner, Sabyasachi Baboo, Patrick Garrett…·John R. Yates
This paper introduces RIPUP, a rapid protease-based workflow for histone PTM analysis, showing improved PTM coverage and quantitative accuracy using TMT labeling and complementary proteases.
DOI 10.1021/acs.analchem.6c01147