Author

Lynne I. McGuire

Roslin InstituteORCID 0000-0001-8917-7264Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Barry Matthew BradfordiD· 1 shared Clare PridansiD· 1 shared David Arthur HumeiD· 1 shared Neil Andrew MabbottiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

Barry Matthew BradfordORCID

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1 paper

Recent·Most cited

Complete microglia deficiency accelerates prion disease without enhancing CNS prion accumulation

Barry Matthew Bradford, Lynne I. McGuire, David Arthur Hume, Clare Pridans, Neil Andrew Mabbott

This study shows that complete microglia deficiency accelerates CNS prion disease without increasing prion accumulation, suggesting microglia protect against astrocyte-driven pathology rather than clearing prions.

Glia · Jul 19, 2022Peer-reviewedNeuroscience