Author

Thomas Mayer

Technical University of MunichORCID 0000-0001-8918-2979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Friedrich Christian SimmeliD· 2 shared Chris ThachukiD· 1 shared Henning HellmeriD· 1 shared Lea BauersachsiD· 1 shared Tiernan KennedyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersBiophysics

Friedrich Christian SimmelORCID

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2 papers

Recent·Most cited

BiophysicsNucleic Acids ResearchPeer-reviewedApr 15, 2026

Operating CRISPR/Cas12a in a complex nucleic acid sequence background

Henning Hellmer, Thomas Mayer, Lea Bauersachs, Friedrich Christian Simmel

This study investigates how background nucleic acids affect CRISPR-Cas12a activity, finding that guide RNA GC content and purine fraction influence kinetic inhibition.

1 citation

experimental assay

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BioengineeringbioRxivPreprintJun 28, 2025

Systematic non-natural base-pairs for strand displacement circuits in complex environments

Tiernan Kennedy, Thomas Mayer, Friedrich Christian Simmel, Chris Thachuk

This study introduces non-natural bases to improve the robustness of strand displacement circuits in complex environments.

DOI 10.1101/2025.06.28.662084

DNA methylationexperimental assay

𝕏 PostBluesky