Author

James M. Aramini

University of TorontoORCID 0000-0001-8926-4210Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexander I. M. SeveriD· 1 shared Hanlin WangiD· 1 shared Huaying ZhaoiD· 1 shared Jeffrey P. BoniniD· 1 shared John L. RubinsteiniD· 1 shared Lewis E. KayiD· 1 shared Peter SchuckiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Alexander I. M. SeverORCID

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1 paper

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedAug 3, 2026

The dynamic and heterogeneous structure of the non-canonical inflammasome

Alexander I. M. Sever, James M. Aramini, Jeffrey P. Bonin…·Lewis E. Kay

This paper determines the structure and dynamics of the non-canonical inflammasome using biophysical methods, showing it is heterogeneous and primed for rapid substrate cleavage.

3 citationstop 3%

humanmouse

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