Leander Meuris

This study investigates combining dexamethasone with PPAR agonist GW7647 to improve glucocorticoid efficacy and reduce metabolic side effects in rheumatoid arthritis models.

The paper shows that low DMSO concentrations skew T cell differentiation towards a memory phenotype during in vitro expansion.

This study benchmarks DNA methylation deconvolution methods for tumoral fraction estimation in cfDNA, finding CelFiE most accurate and introducing DecoNFlow as a comprehensive pipeline.

This study develops and tests dried food-formulated yeast-secreted VHH antibodies as prophylaxis against Clostridioides difficile disease in mice, showing high efficacy in preventing mortality and disease.

This study identifies SopB-associated host proteins using Virotrap, revealing SopB's interaction with ESCRT-0 and its role in Salmonella's manipulation of host endosomal trafficking.

The paper develops an open-source yeast chassis, OPENPichia, for synthetic biology by reverse engineering and characterizing industrial Pichia strains.