Roger I. Calderon

The paper identifies variants in Mycobacterium tuberculosis associated with decreased virulence gene expression and increased transmissibility, particularly in drug-resistant strains.

This study finds that higher Native Peruvian ancestry is associated with increased tuberculosis progression risk, independent of socio-demographic and environmental factors.

The paper investigates the association between dysglycemia and Mycobacterium tuberculosis lineages in TB patients, finding specific lineages linked to diabetes and pre-diabetes comorbidities.

The paper identifies a genetic variant on 3q23 associated with early progression from Mycobacterium tuberculosis exposure to active tuberculosis in Peruvians, showing higher heritability than general TB susceptibility.

A common missense variant in FBN1 reduces height by 2.2 cm in Peruvians, showing strong positive selection and higher frequency in coastal Native American populations.