Katherine E. Irwin

This study identifies brain region-specific TDP-43 pathology patterns in ageing, Alzheimer's disease, and amyotrophic lateral sclerosis, showing strong correlations with ferritin levels as a potential biomarker.

The paper uses large-scale RNA-seq data to show that ciclopirox triggers TDP-43 cryptic exon inclusion through oxidative stress and heavy metal toxicity.

The paper identifies a fluid biomarker, cryptic HDGFL2, that detects early TDP-43 splicing repression in pre-symptomatic ALS patients.

This paper describes retinal development and remodeling in the brown anole lizard, identifying key features of fovea formation and its relationship to eye shape changes.

The paper examines ocular shape changes during development in two foveated reptiles, finding asymmetric elongation and retraction linked to fovea formation and photoreceptor packing.

This paper provides a detailed histological analysis of anterior eye development in the brown anole, Anolis sagrei, highlighting unique structural features compared to mammals and birds.