Author

Kenneth Weke

University of VictoriaORCID 0000-0001-8947-7793Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

David R. GoodlettiD· 2 shared Javier A. AlfaroiD· 2 shared Ajitha RajaniD· 1 shared Aleksander PałkowskiiD· 1 shared Alexander LairdiD· 1 shared Alexandre Giraud-GatineauiD· 1 shared Bo Ren· 1 shared Cátia PesquitaiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

David R. GoodlettORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 7, 2026

Informatics Methods to Enhance Bacterial Peptide Detection

Bo Ren, Kenneth Weke, David R. Goodlett, Javier A. Alfaro

The paper develops and benchmarks an in silico spectral library workflow to detect low-abundance bacterial peptides in human-dominated samples, finding it has complementary performance to conventional database searches.

DOI 10.64898/2026.10.06.757124

bacteria (other)proteomics

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MicrobiologybioRxivPreprintJun 29, 2026

Host adaptation drives genome evolution and virulence diversification in a bacterial zoonotic pathogen

Alexandre Giraud-Gatineau, Kenneth Weke, Rania Ouazahrou…·Mathieu Picardeau

The paper examines how host adaptation influences genome evolution and virulence in Leptospira interrogans, showing distinct genetic and regulatory changes in rodent- and cattle-associated lineages.

DOI 10.64898/2026.06.29.734755

bacteria (other)whole-genome sequencing

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BioinformaticsbioRxivPreprintJan 13, 2022

The immunopeptidome from a genomic perspective: Establishing immune-relevant regions for cancer vaccine design

Georges Bedran, Tongjie Wang, Dominika Pankanin…·Javier A. Alfaro

The paper develops COD-dipp to map MHC Class I antigens from cancer studies and identifies immune-relevant genomic regions for vaccine design.

3 citations

humanproteomics

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