Author

Hagay Ladany

Technion – Israel Institute of TechnologyORCID 0000-0001-8953-6802Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander GuseviD· 1 shared Alon RavidiD· 1 shared Danielle Klinger· 1 shared Dina Schneidman‐DuhovnyiD· 1 shared Ehud BanneiD· 1 shared Esther S. BrielleiD· 1 shared Limor Kalfon· 1 shared Michal Linial BiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alexander GusevORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 31, 2026

Breaking the sparsity barrier in clinical targeted-panel sequencing: Mapping the inherited determinants of mutational signatures

Alon Ravid, Hagay Ladany, Alexander Gusev, Yosef E. Maruvka

This paper introduces GroupSig, a framework to overcome sparsity in clinical targeted-panel sequencing data, identifying inherited determinants of mutational signatures in cancer.

DOI 10.64898/2026.03.29.714525

humanwhole-exome sequencing

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GeneticsAmerican Journal of Medical Genetics Part B Neuropsychiatric GeneticsPeer-reviewedAug 19, 2020

Structural analysis of de novo STXBP1 mutation in complex with syntaxin 1A reveals a major alteration in the interaction interface in a child with developmental delay and spasticity

Ehud Banne, Tzipora C. Falik Zaccai, Esther S. Brielle…·Michal Linial B

The paper identifies a de novo STXBP1 mutation in a child with developmental delay and spasticity, showing how it disrupts the STXBP1-syntaxin 1A interaction through structural analysis.

8 citations

humanprotein structure

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