Cancer BiologybioRxivPreprint
Breaking the sparsity barrier in clinical targeted-panel sequencing: Mapping the inherited determinants of mutational signatures
Alon Ravid, Hagay Ladany, Alexander Gusev, Yosef E. Maruvka
This paper introduces GroupSig, a framework to overcome sparsity in clinical targeted-panel sequencing data, identifying inherited determinants of mutational signatures in cancer.
DOI 10.64898/2026.03.29.714525