BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Lecanemab Blocks the Effects of the Aβ/Fibrinogen Complex on Blood Clots and Synapse Toxicity in Organotypic Culture
Pradeep Kumar Singh, Elisa Nicoloso Simões Pires, Zu‐Lin Chen…·Erin H. Norris
This study shows lecanemab blocks Aβ/fibrinogen complex formation, reducing clot abnormalities and synaptotoxicity in AD models.
19 citations