Vassilis G. Gorgoulis

The paper investigates immune cell senescence in melanoma patients and finds that non-responders to immunotherapy have higher senescence in immune cells compared to responders.

This study compares the effects of aerobic exercise and dietary restriction on liver senescence in mice with diet-induced MASLD, finding that dietary restriction is more effective than exercise alone.

The paper investigates the role of oligodendroglial-derived extracellular vesicles in spreading pathology in MSA-like models, showing they carry pathological Synuclein and TPPP/p25 and induce disease in animal models.

This paper proposes a machine learning approach to estimate drug development risk more accurately than traditional models.

The paper uses deep learning and association rule mining to predict drug response in cancer cell lines, outperforming existing methods and demonstrating a novel approach for therapeutic target identification.