Miranda R. Sun

This study investigates the role of Fibronectin 1 in suture patency and its dysregulation in craniosynostosis models in mice, identifying FN1 as a key regulator of calvarial growth and cell differentiation.

This study identifies Frem1 as a target of Sonic Hedgehog signaling in cranial neural crest cells, showing its role in midfacial morphogenesis and face shape variation.

The paper identifies a genetic modifier, FAT4, associated with left-sided cleft lip and palate, suggesting genetic factors differ from epidemiological patterns.

The paper identifies coding de novo mutations in whole-genome sequencing data from OFC cases and finds enrichment in genes expressed in craniofacial tissues and linked to OFC syndromes.