Author

Jacqueline M. McCabe

Johns Hopkins UniversityORCID 0000-0001-9032-5359Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

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Daniel J. LeahyiD· 1 shared Haley N. CartwrightiD· 1 shared Mónica González-MagaldiiD· 1 shared Ningze Sun· 1 shared

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2020-2020 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Daniel J. LeahyORCID

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1 paper

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Molecular BiologyBiochemical JournalPeer-reviewedOct 12, 2020

Conserved Roles for Receptor Tyrosine Kinase Extracellular Regions in Regulating Receptor and Pathway Activity

Mónica González-Magaldi, Jacqueline M. McCabe, Haley N. Cartwright…·Daniel J. Leahy

The paper shows that the extracellular regions of RTKs regulate downstream signaling, with EGFR extracellular regions activating multiple RTK classes, while Fc-RTK chimeras fail to activate effectors.

9 citations

experimental assay

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